Company Filing History:
Years Active: 1976-1983
Title: **Innovative Contributions of Yao Hua Wu in Pharmaceutical Patents**
Introduction
Yao Hua Wu is a distinguished inventor based in Evansville, Indiana, renowned for his significant contributions to the field of pharmaceuticals. With an impressive portfolio of 15 patents, Wu has made remarkable advancements in the development of compounds that exhibit vital therapeutic properties.
Latest Patents
His recent work involves the discovery of iminopyrrolidinylindoles - N-Phenyl amidines, which are characterized by their diuretic, antithrombogenic, smooth muscle relaxant, anti-inflammatory, and antiarrhythmic properties. These compounds are synthesized by reacting a substituted aniline with a carboxamide, which includes amides and lactams, in the presence of phosphorus oxychloride. Wu's innovative approach has led to the generation of various substituted N-phenyl amidines, such as 5-methyl-2-(N-phenylbenzylamino)-1-pyrroline and 2-(N-phenylbenzylamino)-1-pyrroline. Notably, these indole substituted N-phenyl amidines can be rearranged to produce iminopyrrolinidinylindoles, presenting exciting possibilities in the clinical treatment realm.
Career Highlights
Yao Hua Wu is currently employed at Mead Johnson & Company, where he continues to push the boundaries of pharmaceutical innovation. His research focuses on the synthesis and application of compounds that hold potential for significant health benefits. His extensive patent portfolio stands as a testament to his impactful career and dedication to improving therapeutic solutions.
Collaborations
Throughout his career, Wu has collaborated with fellow innovators like Walter G. Lobeck, Jr., and James W. Rayburn. These partnerships have facilitated the exchange of ideas and expertise, leading to groundbreaking developments in their respective fields.
Conclusion
Yao Hua Wu exemplifies the spirit of innovation in the pharmaceutical industry. His pioneering work in discovering novel compounds with therapeutic properties not only highlights his expertise but also contributes to the advancement of medical science. As he continues to thrive in his career, the impact of his inventions is sure to resonate within the healthcare community for years to come.