Wexford, PA, United States of America

Yangping Yu



 

Average Co-Inventor Count = 6.0

ph-index = 1

Forward Citations = 7(Granted Patents)


Company Filing History:


Years Active: 2018-2021

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5 patents (USPTO):Explore Patents

Title: Innovations of Yangping Yu in Prostate Cancer Research

Introduction

Yangping Yu is a notable inventor based in Wexford, PA (US), recognized for his significant contributions to the field of prostate cancer research. He holds a total of 5 patents, showcasing his innovative approach to understanding and treating this prevalent disease.

Latest Patents

One of Yangping Yu's latest patents focuses on fusion genes associated with progressive prostate cancer. This invention relates to methods and compositions for determining whether a subject with prostate cancer is at greater risk of developing progressive disease. It is based on the discovery that approximately 90% of men carrying specific fusion genes, such as TRMT11-GRIK2 and MTOR-TP53BP1, experienced severe outcomes like recurrence and metastases after radical prostatectomy. In contrast, only 36% of men without these fusion genes faced similar outcomes. Furthermore, the research indicates that no patient studied survived five years without recurrence if their primary prostate cancer contained the TRMT11-GRIK2 or MTOR-TP53BP1 fusion gene. Additionally, the protein encoded by the MAN2A1-FER fusion gene exhibits kinase activity, further emphasizing the importance of these genetic markers in prostate cancer prognosis.

Career Highlights

Yangping Yu is affiliated with the University of Pittsburgh, where he continues to advance his research in cancer genetics. His work has garnered attention for its potential to improve patient outcomes through early detection and targeted treatment strategies.

Collaborations

Yangping Yu collaborates with esteemed colleagues, including Jianhua Luo and Joel Byron Nelson, to enhance the impact of his research. Their combined expertise contributes to a deeper understanding of the genetic factors influencing prostate cancer progression.

Conclusion

Yangping Yu's innovative research and patents significantly contribute to the field of prostate cancer, offering hope for improved diagnostic and treatment methods. His work exemplifies the critical role of genetic research in advancing medical science and patient care.

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