Company Filing History:
Years Active: 2024-2025
Title: Innovations of Yang Zhao in Circular RNA Technology
Introduction
Yang Zhao is a prominent inventor based in Suzhou, China. He has made significant contributions to the field of biotechnology, particularly in the development of recombinant nucleic acid molecules. With a total of 2 patents, his work focuses on advancing the preparation and application of circular RNA.
Latest Patents
Yang Zhao's latest patents include groundbreaking innovations in the preparation of circular RNA. The first patent, titled "Recombinant nucleic acid molecule and application thereof in preparation of circular RNA," introduces a novel recombinant nucleic acid molecule designed to enhance the accuracy and efficiency of circular RNA production. This invention provides a Clean PIE system that minimizes the introduction of additional exon sequences, thereby improving the sequence accuracy and reducing immunogenicity. The applications of this technology are promising in the fields of nucleic acid vaccines, therapeutic protein expression, and gene therapy.
The second patent, "Recombinant nucleic acid molecule based on point mutation of translation initiation element and use thereof in preparation of circular RNA," further refines the process of circular RNA preparation. This invention also utilizes a Clean PIE system, focusing on point mutations to enhance the preparation process. It aims to improve the sequence accuracy and reduce secondary structure changes, which are crucial for the effective application of circular RNA in various therapeutic contexts.
Career Highlights
Yang Zhao is currently employed at Purecodon Biopharma Ltd., a company based in Hong Kong. His role involves pioneering research and development in the field of biopharmaceuticals, particularly focusing on RNA technologies. His innovative work has positioned him as a key figure in the biotechnology sector.
Collaborations
Yang Zhao collaborates with notable colleagues, including Zonghao Qiu and Qiangbo Hou. Together, they contribute to advancing research in the field of circular RNA and its applications.
Conclusion
Yang Zhao's contributions to the field of circular RNA technology are noteworthy and have significant implications for future biotechnological advancements. His innovative patents reflect a commitment to improving the accuracy and efficacy of RNA-based therapies.