Yan Ling Phyllicia Toh

Title: Yan Ling Phyllicia Toh: Innovator in Chromatography Methods

Introduction

Yan Ling Phyllicia Toh is a notable inventor based in Singapore, recognized for his contributions to the field of chromatography. He has developed innovative methods that enhance the performance of purification processes for proteins, which are crucial in various biotechnological applications.

Latest Patents

Toh holds a patent for a method of enhancing the performance of chromatography methods for the purification of proteins. This patent describes compositions, kits, and methods for effectively removing contaminants from protein preparations, such as those derived from cell culture harvests containing recombinant proteins. The method involves contacting a protein preparation with a combination of allantoin, a cationic polymer, and a fatty acid, leading to the formation of solids that can be removed through suitable processes. Further treatment with a chemically reactive surface enhances the results achieved in the initial purification step.

Career Highlights

Toh is affiliated with the Agency for Science, Technology and Research, where he applies his expertise in chromatography and protein purification. His work has significant implications for improving the efficiency and effectiveness of protein purification techniques, which are vital in research and pharmaceutical development.

Collaborations

Toh has collaborated with esteemed colleagues, including Peter Stanley Gagnon and Wei Zhang, contributing to advancements in their shared field of research.

Conclusion

Yan Ling Phyllicia Toh's innovative work in chromatography methods exemplifies the importance of scientific research in enhancing protein purification processes. His contributions continue to impact the biotechnology industry positively.