Title: Yan Lan - Innovator in Immune Therapy
Introduction
Yan Lan is a notable inventor based in the United States, recognized for his contributions to the field of targeted immune therapy. His innovative work focuses on the development of heterodimeric fusion proteins that have significant implications for immune stimulation.
Latest Patents
Yan Lan holds a patent titled "Heterodimeric Fusion Proteins Useful For Targeted Immune Therapy And General Immune Stimulation." This patent discloses methods for producing fusion proteins with the heterodimeric cytokine interleukin-12. The process involves a specific stepwise approach to genetic engineering, ensuring the proper ratio of fused and non-fused subunits in the fusion protein. The method includes expressing the non-fused p40 IL-12 subunit in a production cell line, followed by or simultaneously expressing a second recombinant fusion protein consisting of the fused polypeptide linked to the p35 subunit of IL-12. This innovative approach guarantees the production of active heterodimeric fusion proteins.
Career Highlights
Throughout his career, Yan Lan has worked with various organizations, including Emd Lexigen Research Center Corporation and Stephen D. Gillies. His experience in these companies has contributed to his expertise in the field of immune therapy.
Collaborations
Yan Lan has collaborated with Stephen D. Gillies, further enhancing his research and development efforts in the area of immune stimulation.
Conclusion
Yan Lan's work in the development of heterodimeric fusion proteins represents a significant advancement in targeted immune therapy. His innovative approaches and collaborations have the potential to impact the field of immunology positively.