Yakun Wan

Title: Innovations of Yakun Wan in Biopharmaceuticals

Introduction

Yakun Wan is a prominent inventor based in Shanghai, China, known for his significant contributions to the field of biopharmaceuticals. He holds three patents that showcase his innovative work in antibody development and disease treatment.

Latest Patents

One of his latest patents is an anti-interleukin-4 receptor (IL-4R) single-domain antibody, which includes a coding polynucleotide and methods for making and using the antibody for IL-4R detection and disease treatment. This invention specifically recognizes human and marmoset IL-4R, while not recognizing mouse IL-4R, demonstrating its specificity. The single-domain antibody effectively inhibits the proliferation of TF-1 cells and the activation of the pSTAT6 signaling pathway in cells. Another notable patent is for a blocking type PD-L1 single-domain camel antibody, which can be used for treating, preventing, or diagnosing PD-L1 related diseases such as tumors.

Career Highlights

Yakun Wan is currently associated with Shanghai Novamab Biopharmaceuticals Co., Ltd., where he continues to advance his research and development efforts in the biopharmaceutical sector. His work has positioned him as a key figure in the innovation of therapeutic antibodies.

Collaborations

Yakun collaborates with notable colleagues, including Xiaoning Shen and Min Zhu, who contribute to his research endeavors and enhance the impact of his inventions.

Conclusion

Yakun Wan's innovative work in the field of biopharmaceuticals, particularly in the development of single-domain antibodies, highlights his role as a leading inventor. His contributions are paving the way for advancements in disease treatment and detection.