Location History:
- Warangal, IN (2017)
- Pune, IN (2018)
Company Filing History:
2 out of 2,096 
1 out of 702 
Years Active: 2017-2018
Title: Yadagiri Kommagalla: Innovator in Anti-Inflammatory Compounds
Introduction
Yadagiri Kommagalla is a notable inventor based in Pune, India. He has made significant contributions to the field of medicinal chemistry, particularly in the development of anti-inflammatory compounds. With a total of 2 patents, his work showcases innovative approaches to drug synthesis.
Latest Patents
One of his latest patents is titled "Process for the preparation of anti-inflammatory aroylbenzofuran compounds." This patent discloses an efficient process for synthesizing benzofuran analogs that exhibit anti-inflammatory activity. The process involves Ru-catalyzed branched and linear selective alkylation of aroylbenzofurans with alpha, beta unsaturated esters via C—H activation in the presence of a base, additives, and an organic solvent at suitable temperatures. This method yields high amounts of desired linear and branched alkylated benzofuran compounds.
Another significant patent is for "Small molecule inhibitors of PI3-kinase signaling." This patent provides certain 1,2,3-triazole and 1,2,3-triazole dimer analogs of DM-PIT-1, which are second-generation selective non-phosphoinositide small molecule inhibitors of phosphatidylinositol-3,4,5-trisphosphate (PIP3). The invention includes 1,2,3-triazoles represented by specific formulas, contributing to advancements in targeted cancer therapies.
Career Highlights
Yadagiri has worked with prestigious organizations such as the Council of Scientific & Industrial Research and Tufts University. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Some of his notable coworkers include Chepuri Venkata Ramana and Kolluru Srinivas. Their collaborative efforts have further enhanced the impact of his research and innovations.
Conclusion
Yadagiri Kommagalla's contributions to the field of medicinal chemistry, particularly in anti-inflammatory compounds, highlight his innovative spirit and dedication to advancing healthcare solutions. His patents reflect a commitment to developing effective therapies that can significantly improve patient outcomes.