This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignees: The United States of America as Represented by the Department of Veterans Affair, University of California, University of Michigan. Active years: 2025.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 1 
1 out of 16,035 
1 out of 3,543 
Years Active: 2025
Title: Yacov Koffler: Innovator in Nerve Repair Scaffolds
Introduction
Yacov Koffler is a prominent inventor based in San Diego, CA (US). He is known for his innovative contributions to the field of tissue engineering, particularly in the development of nerve repair scaffolds. His work focuses on enhancing neural tissue growth through advanced materials and methods.
Latest Patents
Koffler holds a patent titled "Nerve repair scaffolds having high microchannel volume and methods for making the same." This patent describes tissue scaffolds designed for neural tissue growth, featuring a plurality of microchannels within a sheath. Each microchannel has a porous wall with a thickness of ≤about 100 μm, made from a biocompatible and biodegradable material, specifically a polyester polymer. The materials used may include polycaprolactone and poly(lactic-co-glycolic acid) polymer, among others. The scaffolds are engineered to have a high open volume percentage, which promotes superior linear and high-fidelity neural tissue growth while minimizing inflammation at the implantation site in vivo. Additionally, the patent outlines methods for creating these scaffolds, including mixing a reduced particle size porogen with a polymeric precursor solution, casting the material onto a template, and processing it to form the final tissue scaffold.
Career Highlights
Throughout his career, Koffler has made significant strides in the field of biomedical engineering. He has worked at esteemed institutions such as the University of Michigan and the University of California, where he has contributed to various research projects and innovations.
Collaborations
Koffler has collaborated with notable colleagues, including Jeffrey S. Sakamoto and Dena Shahriari. These collaborations have furthered his research and development efforts in tissue engineering and nerve repair technologies.
Conclusion
Yacov Koffler's work in developing nerve repair scaffolds represents a significant advancement in the field of tissue engineering. His innovative approaches and patented technologies hold promise for improving neural tissue growth and repair.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile