Location History:
- Maple Glen, PA (US) (2016)
- Ambler, PA (US) (2018)
- Horsham, PA (US) (2014 - 2023)
- Brewster, NY (US) (2024)
Company Filing History:
Years Active: 2014-2024
Title: Innovations of Xunbao Duan in Cancer Treatment
Introduction
Xunbao Duan is a prominent inventor based in Horsham, PA (US), known for his significant contributions to the field of cancer treatment. With a total of 11 patents, his work primarily focuses on developing novel antibodies and bispecific antigen-binding molecules that target specific proteins associated with aggressive tumor growth.
Latest Patents
Duan's latest patents include groundbreaking inventions related to antibodies and bispecific antigen-binding molecules that bind to HER2 and/or APLP2. The human epidermal growth factor 2 (HER2) is a critical protein expressed in breast cancer cells, and its expression is often correlated with aggressive tumor growth. His inventions provide novel full-length human (IgG) antibodies that specifically bind to human HER2 and APLP2. Additionally, he has developed bispecific antibodies that can bind to both HER2 and APLP2, facilitating the internalization and degradation of HER2 in the presence of HER2-expressing tumors. These bispecific antibodies are particularly useful for treating breast cancers, including those classified as IHC2+. Furthermore, Duan's patents also encompass anti-HER2 antibody drug conjugates that inhibit tumor growth in vivo.
Career Highlights
Xunbao Duan is currently employed at Regeneron Pharmaceuticals, Inc., where he continues to innovate in the field of cancer therapeutics. His work has been instrumental in advancing the understanding and treatment of various cancers, particularly those associated with the HER2 protein.
Collaborations
Duan collaborates with notable colleagues, including Douglas MacDonald and Christopher Daly, to further enhance the impact of his research and inventions in the pharmaceutical industry.
Conclusion
Xunbao Duan's innovative work in developing targeted therapies for cancer exemplifies the potential of scientific research to improve treatment outcomes for patients. His contributions to the field are paving the way for more effective cancer therapies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.