Company Filing History:
Years Active: 2004-2005
Title: Innovations of Xun Zhang in Cancer Research
Introduction
Xun Zhang is a notable inventor based in Malden, MA, who has made significant contributions to the field of cancer research. He holds four patents that focus on innovative methods and compositions aimed at inhibiting neoplastic cellular proliferation and transformation.
Latest Patents
One of his latest patents involves antibodies against mouse pituitary tumor transforming gene carboxy-terminal (PTTG-C) peptides. These isolated antibodies specifically bind to murine PTTG-C peptides and are useful in assays to determine levels of PTTG proteins or PTTG-C peptides in various samples. The antibodies can also purify PTTG proteins from crude cell extracts and are considered therapeutically beneficial in counteracting the biological effects of PTTG proteins in vivo.
Another significant patent discloses a method for inhibiting neoplastic cellular proliferation and transformation of mammalian cells. This method utilizes PTTG-C peptides to regulate PTTG expression and function in a dominant negative manner. The invention includes gene-based treatments that deliver PTTG-C-related polynucleotides to inhibit endogenous PTTG expression. Additionally, it covers peptide-based treatments that deliver PTTG-C peptide molecules to inhibit PTTG function. The patent also discusses methods for inhibiting tumor angiogenesis and compositions that include PTTG carboxy-terminal peptides or related polynucleotides.
Career Highlights
Xun Zhang is currently affiliated with Cedars-Sinai Medical Center, where he continues to advance his research in cancer therapeutics. His work has the potential to significantly impact the treatment of tumors and related conditions.
Collaborations
Xun Zhang has collaborated with notable colleagues such as Gregory A. Horwitz and Shlomo Melmed, contributing to the advancement of research in his field.
Conclusion
Xun Zhang's innovative patents and research efforts are paving the way for new therapeutic approaches in cancer treatment. His work exemplifies the critical role of inventors in advancing medical science and improving patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.