Xu Jie-cheng

Title: Xu Jie-cheng: Innovator in Hormonal Peptide Research

Introduction

Xu Jie-cheng is a prominent inventor based in Shanghai, China. He has made significant contributions to the field of hormonal peptides, with a focus on developing super agonists of the luteinizing hormone releasing hormone (LHRH). His innovative work has led to the filing of multiple patents, showcasing his expertise and dedication to advancing medical science.

Latest Patents

Xu Jie-cheng holds 3 patents related to effective hormonal peptides. His latest patents include the synthesis of two sets of hormonal peptides, namely D-3-QA1 6-LHRH and D-3-Pal.sup.6 -LHRH. These peptides are designed to act as super agonists of LHRH, which plays a crucial role in stimulating cell growth in the testes. Notably, one peptide features the D(dextro)-form of a mono-heterocyclic amino acid in position six (D-3-pyridyl-alanine), while the other contains a bi-heterocyclic amino acid in the same position (.beta.-(3-quinolyl)-D-.alpha.-alanine). Both peptides exhibit lower metabolic reactivity compared to previous compounds, while demonstrating significantly greater potency than LHRH itself.

Career Highlights

Xu Jie-cheng is affiliated with the University of Texas System, where he continues to engage in groundbreaking research. His work has not only contributed to the scientific community but has also paved the way for potential therapeutic applications in hormonal treatments.

Collaborations

Throughout his career, Xu Jie-cheng has collaborated with notable colleagues, including Karl A. Folkers and Cyril Y. Bowers. These partnerships have further enriched his research and innovation in the field of hormonal peptides.

Conclusion

Xu Jie-cheng's contributions to the development of hormonal peptides highlight his role as a leading inventor in the field. His innovative patents and collaborations reflect his commitment to advancing medical science and improving therapeutic options.