Xiyuan Sun

Title: Innovations by Xiyuan Sun

Introduction

Xiyuan Sun is an accomplished inventor based in Cleveland, OH (US). He has made significant contributions to the field of analytical systems and genotyping methods. With a total of 2 patents, his work is paving the way for advancements in medical diagnostics.

Latest Patents

Xiyuan Sun's latest patents include an "Analytical system comprising sample management module and method thereof." This invention provides an analytical system that includes a sample management module. A pressure delivery assembly is designed to compress and deform a mixing chamber containing a sample preparation, while simultaneously opening a plug of the mixing chamber to release the sample preparation. This system can be manufactured as a sample box that is combinable with a detector box, making it particularly convenient for patients to use at home, such as for screening colorectal cancer with their fecal samples.

Another notable patent is the "Method for genotyping of single nucleotide polymorphism." The VSET method involves providing a polynucleotide acid sample that includes at least one target site and a first region of nucleotides adjacent to the target site. The method preferably amplifies the polynucleotide and combines it with three dideoxynucleotides and one deoxynucleotide, ensuring that the nucleotide of the deoxynucleotide differs from that in the dideoxynucleotide. The mini-sequencing primer is extended with a complementary base to provide extension products, which are then identified, preferably by MALDI-TOF mass spectrometry. This innovative approach allows for the determination of genotypes at variable sites based on the number of nucleotides in the extension products.

Career Highlights

Xiyuan Sun is affiliated with Cleveland State University, where he continues to engage in research and development in his field. His work has garnered attention for its practical applications in healthcare and diagnostics.

Collaborations

Xiyuan collaborates with Baochuan Guo, who is also a key contributor to his research endeavors. Their partnership enhances the innovative potential of their projects.

Conclusion

Xiyuan Sun's contributions to analytical systems and genotyping methods demonstrate his commitment to advancing medical technology. His patents reflect a dedication to improving patient care and diagnostic processes.