Company Filing History:
Years Active: 2023
Title: Xiujuan Shi: Innovator in Cancer Cell Imaging
Introduction
Xiujuan Shi is a prominent inventor based in Hong Kong, CN. He has made significant contributions to the field of cancer cell imaging through his innovative research and development. His work focuses on the creation of advanced luminogens that exhibit aggregation-induced emission (AIE), which has important applications in medical imaging.
Latest Patents
Xiujuan Shi holds a patent for "AIEgens for cancer cell imaging." This patent describes a luminogen that demonstrates aggregation-induced emission, where T1, T2, and T3 comprise one or more polyynes as a conjugated bridge. The invention also includes an AIEgen featuring a hydrophilic pyridinium group as a strong electron-withdrawing group, a piperazine group as an electron-donating group, and α-Cyanostilbene. The AIEgen is designed to exhibit aggregation-induced emission, which enhances its effectiveness in imaging applications. The patent outlines a method for synthesizing the AIEgen and a labeling method that involves incubating a subject with cells using a conjugate formed by linking the AIEgen with an antibody. This process allows for selective labeling of desired cells through turn-on imaging, which occurs when the cells are stained by the fluorescent emission of the AIEgen after the antibody is degraded post-internalization.
Career Highlights
Xiujuan Shi is affiliated with The Hong Kong University of Science and Technology, where he conducts his research. His work has garnered attention for its potential to improve cancer diagnostics and treatment monitoring. With a focus on innovative imaging techniques, he continues to push the boundaries of what is possible in medical science.
Collaborations
Xiujuan Shi collaborates with esteemed colleagues, including Benzhong Tang and Yee Yung Yu. Their combined expertise contributes to the advancement of research in the field of cancer imaging and therapeutics.
Conclusion
Xiujuan Shi's contributions to cancer cell imaging through his innovative patent demonstrate his commitment to advancing medical science. His work not only enhances our understanding of cancer but also paves the way for improved diagnostic techniques.