Company Filing History:
Years Active: 2004-2010
Title: Innovations of Inventor Xingrong Liu
Introduction
Xingrong Liu is a notable inventor based in Groton, CT (US). He has made significant contributions to the field of pharmaceutical sciences, particularly in the area of drug metabolism and excretion. With a total of 3 patents to his name, Liu's work focuses on methods that enhance the screening of candidate compounds for their susceptibility to biliary excretion.
Latest Patents
Liu's latest patents include innovative methods that streamline the screening process for candidate compounds. One of his patents is titled "Method of screening a metabolite of a parent candidate compound for susceptibility to biliary excretion." This method involves providing a culture of hepatocytes with at least one bile canaliculus, exposing a candidate compound to the culture, and determining the amount of the candidate compound in the bile canaliculus. This amount indicates the susceptibility of the candidate compound to biliary excretion. The method is particularly beneficial for screening multiple candidate compounds simultaneously.
Another significant patent by Liu is "Method of screening candidate compounds for susceptibility to biliary excretion by endogenous transport systems." Similar to his previous patent, this method also utilizes a culture of hepatocytes and focuses on determining the amount of candidate compound in the bile canaliculus. This approach is designed to enhance the efficiency of screening processes in drug development.
Career Highlights
Xingrong Liu is affiliated with the University of North Carolina at Chapel Hill, where he continues to contribute to research and innovation in drug metabolism. His work has been instrumental in advancing methodologies that improve the understanding of how drugs are processed in the body.
Collaborations
Liu has collaborated with esteemed colleagues such as Edward L LeCluyse and Kim L R Brouwer. These collaborations have further enriched his research and have led to advancements in the field of drug metabolism.
Conclusion
Xingrong Liu's innovative methods for screening candidate compounds represent a significant advancement in pharmaceutical research. His contributions are vital for improving drug development processes and enhancing our understanding of drug metabolism.