Xinglu Huang

Title: Innovations of Xinglu Huang in Protein Nanocages

Introduction

Xinglu Huang is an accomplished inventor based in Bethesda, MD, known for his significant contributions to the field of biomedical engineering. His work primarily focuses on the development of advanced drug delivery systems that enhance therapeutic efficacy.

Latest Patents

Huang holds a patent for "Protein nanocages with enhanced mucus penetration for targeted tissue and intracellular delivery." This innovative formulation features protein nanocages designed to improve mucus penetration and colloidal stability. The technology allows for controlled delivery of therapeutic, prophylactic, or diagnostic agents specifically to tumors. The formulation utilizes a dense coating of polyethylene glycol on self-assembled protein nanocages, which enhances distribution at mucosal tissues after topical administration and improves circulation time following intravenous administration. Additionally, the nanocages are engineered to bind to tumor cell receptors, facilitating the release of chemotherapeutic agents after uptake by the tumor cells. This method demonstrates improved efficacy compared to traditional carrier-free agents.

Career Highlights

Xinglu Huang is affiliated with The Johns Hopkins University, where he continues to advance research in drug delivery systems. His innovative approaches have garnered attention in the scientific community, contributing to the development of more effective treatment options for cancer patients.

Collaborations

Huang collaborates with notable colleagues, including Jung Soo Suk and Justin Scot Hanes, who share his commitment to enhancing drug delivery technologies.

Conclusion

Xinglu Huang's work in developing protein nanocages represents a significant advancement in targeted drug delivery systems. His innovative approach has the potential to improve treatment outcomes for patients with tumors, showcasing the importance of continued research in this vital area of medicine.