This inventor holds 2 USPTO granted patents and 1 published patent application, plus 1 CIPO patent and 1 EPO patent. Top assignee: Louisiana State University and Agricultural & Mechanical College. Active years: 2016-2017.
Company Filing History:
Years Active: 2016-2017
Title: Innovations by Inventor Xinggui Shen
Introduction
Xinggui Shen is a notable inventor based in Shreveport, Louisiana. He has made significant contributions to the field of biomedical research, particularly in the area of hydrogen sulfide measurement and its implications for cardiovascular health. With a total of 2 patents, his work is paving the way for advancements in clinical diagnostics.
Latest Patents
Xinggui Shen's latest patents focus on the measurement and implications of hydrogen sulfide (HS) levels in plasma. One of his patents highlights that HS levels are useful in diagnosing cardiovascular disease. Additionally, the ratio of HS to nitric oxide (NO) in plasma can aid in diagnosing peripheral artery disease. Another significant patent involves a method to measure biologically labile hydrogen sulfide pools. This innovative method allows for the selective liberation, trapping, and derivatization of labile hydrogen sulfide. By using a reducing agent, TCEP (Tris(2-carboxyethyl)phosphine hydrochloride), disulfide bonds are reduced in an acid solution, enabling the measurement of free hydrogen sulfide, acid-labile sulfide, and bound sulfane sulfur. This method has been successfully applied to blood samples from both mice and humans, demonstrating its potential for research, environmental, and clinical diagnostic purposes.
Career Highlights
Xinggui Shen is affiliated with Louisiana State University and Agricultural & Mechanical College, where he continues to engage in groundbreaking research. His work has garnered attention for its innovative approach to understanding hydrogen sulfide bioavailability in biological samples.
Collaborations
Some of his notable coworkers include Christopher Kevil and Elvis A Peter, who contribute to the collaborative research environment at Louisiana State University.
Conclusion
Xinggui Shen's contributions to the field of biomedical research through his patents on hydrogen sulfide measurement are significant. His work not only enhances our understanding of cardiovascular health but also opens new avenues for clinical diagnostics.