Xing-Zheng Wu

Title: Innovations in Fluorescence Measurement by Xing-Zheng Wu

Introduction

Xing-Zheng Wu is a notable inventor based in Fukui, Japan. He has made significant contributions to the field of fluorescence measurement, particularly through his innovative patent that enhances the detection of proteins.

Latest Patents

Wu holds a patent for the "Measurement of fluorescence using capillary isoelectric focusing." This improved apparatus facilitates axially illuminated laser-induced fluorescence whole-column imaging detection in the capillary isoelectric focusing of proteins. The design incorporates a separation capillary made of low refractive index Teflon, conditioned with methylcellulose to minimize electroosmotic flow. Additionally, a small amount of high refractive index organic solvent, glycerol, is added to the sample mixture. The axially directed laser excitation beam is propagated with total internal reflection, significantly reducing interference from stray light or scattering light from the capillary wall. With the naturally fluorescent protein R-phycoerythrin, a concentration detection limit of LOD 10M or mass LOD 10Mo was achieved.

Career Highlights

Throughout his career, Wu has focused on advancing techniques in fluorescence measurement. His innovative approaches have led to improved detection methods that are crucial for various applications in biochemistry and molecular biology.

Collaborations

Wu has collaborated with esteemed colleagues, including Janusz Boleslaw Pawliszyn and Tiemin Huang. Their combined expertise has contributed to the development of advanced methodologies in the field.

Conclusion

Xing-Zheng Wu's contributions to fluorescence measurement through his innovative patent demonstrate his commitment to advancing scientific research. His work continues to influence the field and enhance detection techniques for proteins.