This inventor holds 3 USPTO granted patents and 2 published patent applications. Top assignee: Life Technologies Corporation. Active years: 2020-2023.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- San Marcos, CA (US) (2020 - 2022)
- Zhangiagang, CN (2023)
Company Filing History:
Years Active: 2020-2023
Title: Innovations by Inventor Xin Yu
Introduction
Xin Yu is a notable inventor based in San Marcos, CA (US). He has made significant contributions to the field of viral vector production, holding a total of 3 patents. His work focuses on developing advanced systems for producing adeno-associated viruses (AAV) and lentiviral vectors, which are crucial for gene therapy applications.
Latest Patents
One of Xin Yu's latest patents is a "Suspension system for adeno associated virus production." This technology relates to a production system designed to produce AAV vectors in a serum-free suspension platform and at high titers. The system utilizes reagents such as media, cells, transfection reagent, AAV enhancer, and a lysis buffer, all aimed at maximizing AAV production from suspension cultures of mammalian cells, specifically HEK293 cells. With this innovative system, it is possible to deliver up to about 2×10 viral genomes per milliliter (vg/mL) of unconcentrated AAV vectors.
Another significant patent is the "Serum-free suspension system for lentiviral production." This system comprises a lentiviral culture supplement to control cell growth, a transfection reagent that includes DHDMS, DOPE, and cholesterol to enhance transfection efficiency, and a lentiviral production enhancer made up of sodium propionate, sodium butyrate, and caffeine to boost lentiviral production. The method for lentiviral vector production involves culturing eukaryotic cells in a serum-free medium and transfecting them with a lentiviral vector using the aforementioned transfection reagent.
Career Highlights
Xin Yu is currently employed at Life Technologies Corporation, where he continues to innovate in the field of viral vector production. His work has been instrumental in advancing the capabilities of gene therapy technologies.
Collaborations
Xin Yu collaborates with talented individuals such as Xavier De Mollerat Du Jeu and Xiquan Liang, who contribute to the success of his projects and innovations.
Conclusion
Xin Yu's contributions to the field of viral vector production are significant and impactful. His innovative patents and work at Life Technologies Corporation highlight his dedication to advancing gene therapy technologies.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile