This inventor holds 1 USPTO granted patent. Top assignee: Johns Hopkins University. Active years: 2022.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2022
Title: Innovations of Xin Yi Chan in Vascular Network Assembly
Introduction
Xin Yi Chan is an accomplished inventor based in Baltimore, MD (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of three-dimensional vascular networks. His innovative work focuses on utilizing induced pluripotent stem cells to create functional vascular structures.
Latest Patents
Xin Yi Chan holds a patent for a groundbreaking invention titled "Three-dimensional vascular network assembly from induced pluripotent stem cells." This patent describes a method for generating early vascular cells (EVCs), including endothelial cells and pericytes, from human induced pluripotent stem cells (hiPSCs). Unlike isolated endothelial progenitor cells, the differentiated endothelial cells mature and exhibit functionality. When encapsulated in synthetic hydrogel, these EVCs respond to matrix cues and self-assemble to form complex three-dimensional networks. Additionally, they can adapt to hypoxic microenvironments and undergo vasculogenesis, further enhancing their utility in tissue engineering.
Career Highlights
Xin Yi Chan is affiliated with The Johns Hopkins University, where he conducts his research and development work. His innovative approach to creating vascular networks has the potential to revolutionize regenerative medicine and tissue engineering. His research is pivotal in addressing challenges related to vascularization in engineered tissues.
Collaborations
Xin Yi Chan collaborates with notable colleagues, including Sharon Gerecht and Quinton Smith. These partnerships enhance the interdisciplinary nature of his research and contribute to the advancement of knowledge in the field.
Conclusion
Xin Yi Chan's work in the assembly of three-dimensional vascular networks from induced pluripotent stem cells represents a significant advancement in biomedical engineering. His innovative approaches and collaborations are paving the way for future breakthroughs in regenerative medicine.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile