Company Filing History:
Years Active: 2001-2002
Title: Innovations of Xilin Zhao in Antimicrobial and Antiviral Drug Development.
Introduction
Xilin Zhao is a notable inventor based in Mt. Vernon, NY (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of antimicrobial and antiviral drugs. With a total of 2 patents to his name, Zhao's work focuses on addressing the challenges of drug resistance in pathogens.
Latest Patents
Zhao's latest patents revolve around the dosing and development of antimicrobial and antiviral drugs determined by the restriction of resistant mutant selection. His research has led to the discovery of a concentration of drugs, known as the "mutant prevention concentration" (MPC), at which drug-resistant mutant pathogen strains are not selected. Maintaining serum concentrations of the drug above the MPC throughout treatment is crucial for limiting the selection of drug-resistant mutants. Furthermore, Zhao identified a "mutant selection window" (MSW) where drug-resistant mutants are exclusively selected. He introduced a quantitative expression called the "window index" (WI), defined as the ratio of the MPC to the minimum inhibitory concentration (MIC). This window index is characteristic of specific drugs and pathogens.
Career Highlights
Zhao's career is marked by his dedication to public health and innovative research. He works at the Public Health Research Institute of the City of New York, Inc., where he collaborates with other experts in the field. His work has the potential to significantly impact the treatment of infections caused by resistant pathogens.
Collaborations
Zhao has collaborated with notable colleagues, including Yuzhi Dong and Karl A Drlica. These partnerships have enhanced the research and development of effective antimicrobial and antiviral therapies.
Conclusion
Xilin Zhao's contributions to the field of drug development are invaluable, particularly in combating drug resistance. His innovative approaches and discoveries pave the way for more effective treatments in public health.