Location History:
- East Haven, CT (US) (2001 - 2002)
- Belle Meade, NJ (US) (2002 - 2003)
- Bridgewater, NJ (US) (2004 - 2005)
Company Filing History:
Years Active: 2001-2005
Title: Innovations of Xiaoyan Zhang in C5a Receptor Modulation
Introduction
Xiaoyan Zhang is a prominent inventor based in Bridgewater, NJ (US). She has made significant contributions to the field of pharmaceutical sciences, particularly in the development of small molecule modulators for C5a receptors. With a total of 7 patents to her name, her work has the potential to impact the treatment of various inflammatory and immune system disorders.
Latest Patents
One of Xiaoyan Zhang's latest patents focuses on high affinity small molecule C5a receptor modulators. This invention pertains to low molecular weight, non-peptidic, non-peptidomimetic organic molecules that serve as modulators of mammalian complement C5a receptors. The preferred compounds exhibit properties such as being multi-aryl or heteroaryl in structure, having a detectable in vitro effect at a pharmaceutically acceptable oral dose, and being capable of inhibiting leukocyte chemotaxis at nanomolar concentrations. Additionally, these compounds can be utilized in pharmaceutical compositions for treating a variety of inflammatory and immune system disorders.
Career Highlights
Xiaoyan Zhang is currently associated with Neurogen Corporation, where she continues to innovate in the field of drug development. Her research has led to advancements in understanding how to effectively target C5a receptors, which are crucial in the immune response.
Collaborations
Xiaoyan has collaborated with notable colleagues such as Andrew Y Thurkauf and He Zhao, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Xiaoyan Zhang's work in developing high affinity small molecule C5a receptor modulators showcases her commitment to advancing pharmaceutical science. Her contributions are paving the way for new treatments for inflammatory and immune system disorders.