Xiaoling Tang

Title: The Innovative Contributions of Inventor Xiaoling Tang

Introduction

Xiaoling Tang, an accomplished inventor based in Hangzhou, China, is recognized for her significant contributions in the field of bioengineering. With her expertise, she has successfully developed a mutant nitrilase that advances the synthesis of pharmaceutical intermediates, showcasing the potential of her inventions to reshape industrial applications.

Latest Patents

Xiaoling Tang holds a patent for her innovative work titled "Nitrilase mutant, construction method therefor, and application thereof." This invention reveals a nitrilase mutant and its construction method, focusing on its application in the synthesis of chiral intermediates of pregabalin. By utilizing peptide fragment displacement methods on turnip nitrilase (BrNIT) and Arabidopsis nitrilase (AtNIT), she successfully created mutants that exhibit enhanced catalytic activity and stereoselectivity compared to their wild-type counterparts. This advancement is poised to meet the demands of industrial applications, particularly in efficiently catalyzing racemic IBSN to produce 3-cyano-5-methylhexanoic acid.

Career Highlights

Xiaoling Tang's career is distinguished by her groundbreaking research at Zhejiang University, where she has contributed to various projects aimed at improving biocatalysis processes. Her work not only emphasizes innovation in enzyme engineering but also highlights her commitment to advancing scientific knowledge in bioengineering applications.

Collaborations

Throughout her career, Xiaoling has collaborated with esteemed colleagues, including Renchao Zheng and Yuguo Zheng. These partnerships have fostered a dynamic research environment, allowing for the exchange of ideas and collaborative efforts that have produced innovative solutions in the bioengineering domain.

Conclusion

Xiaoling Tang stands out as a pioneering inventor, making remarkable strides in the field of bioengineering. Her patented nitrilase mutant represents a significant milestone in the synthesis of pharmaceutical intermediates, demonstrating her capability to create impactful innovations. As she continues to explore new horizons in her research, the academic and industrial communities can look forward to further advancements driven by her inventive spirit.