Company Filing History:
Years Active: 2022-2025
Title: Innovations of Xiaofeng Liu
Introduction
Xiaofeng Liu is a prominent inventor based in Slough, GB. He has made significant contributions to the field of antibody design and treatment of IgE-mediated disorders. With a total of 5 patents, Liu's work has the potential to impact various medical applications.
Latest Patents
Liu's latest patents include innovative methods for de novo antibody design. This patent discloses computer-implemented methods for designing antibodies that bind to target epitopes. The method involves identifying hotspot residues that correspond to hotspot sites on the target epitope. Candidate antibody structures are selected from a database, ensuring that characteristic atoms can be superimposed computationally with minimal spatial deviation. The designed antibody is generated by replacing matching residues to enhance predicted affinity.
Another significant patent focuses on improved anti-IgE antibodies and antigen binding agents. This invention targets IgE, which is crucial for treating disorders caused by IgE, such as allergic responses and certain autoimmune disorders. The improved anti-IgE antibodies may exhibit enhanced affinity for IgE and better interaction with the Cε2 domain of IgE. This innovation aims to provide novel treatments for IgE-mediated disorders by effectively targeting free IgE and IgE complexed with the FcεRI receptor.
Career Highlights
Xiaofeng Liu is currently employed at Ucbbiopharma Srl, where he continues to advance his research in antibody design and treatment methodologies. His work is characterized by a commitment to improving therapeutic options for patients suffering from IgE-related conditions.
Collaborations
Liu collaborates with notable colleagues, including Terence Seward Baker and Ralph Adams. Their combined expertise contributes to the innovative research and development efforts at Ucbbiopharma Srl.
Conclusion
Xiaofeng Liu's contributions to the field of antibody design and treatment of IgE-mediated disorders highlight his role as a leading inventor. His innovative patents and ongoing research promise to enhance therapeutic strategies in the medical field.