Company Filing History:
Years Active: 2021
Title: Innovations by Xiaocong Guan in Cancer Treatment
Introduction
Xiaocong Guan is an inventive researcher based in Shanghai, China, who has made significant contributions in the field of medicinal chemistry. He has been instrumental in developing advanced compounds that hold promise for cancer treatment, particularly in targeting specific pathways involved in tumor growth.
Latest Patents
Xiaocong Guan holds a patent for an "O-aminoheteroaryl alkynyl-containing compound, preparation method therefor, and use thereof." This compound is outlined by a specific structure that exhibits notable advantages, such as high inhibitory activity against both FGFR and RET targets, while maintaining relatively low activity against KDR. The compound has shown strong inhibitory effects in various cancer cell lines, including human lung cancer cells (NCI-H1581) and gastric cancer cells (SNU16). The pharmacokinetic studies indicate that this compound is druggable and has demonstrated significant tumor growth inhibition in long-term animal models.
Career Highlights
As a researcher affiliated with the Chinese Academy of Sciences, Xiaocong Guan has focused on synthesizing innovative compounds with therapeutic applications. His work is characterized by a commitment to translating laboratory findings into practical treatments for cancer patients.
Collaborations
Throughout his career, Xiaocong Guan has collaborated with distinguished peers such as Youhong Hu and Meiyu Geng. Together, they have combined their expertise to explore new frontiers in cancer therapy and contribute to the scientific community's understanding of targeted treatment options.
Conclusion
Xiaocong Guan's patent demonstrates the potential of innovative compounds in treating cancers that are resistant to conventional therapies. His dedication to research at the Chinese Academy of Sciences and collaborations with other experts highlights the importance of teamwork in advancing medical science. The implications of his work extend beyond academic interest, providing hope for effective cancer therapies in the future.
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