Company Filing History:
Years Active: 2017
Title: The Innovative Contributions of Inventor Xiaobing Zhang
Introduction
Xiaobing Zhang, based in Loma Linda, CA, is a distinguished inventor known for his groundbreaking work in the field of regenerative medicine. His innovative approach focuses on creating effective methods for generating induced pluripotent stem cells, a technology with immense potential for medical research and applications.
Latest Patents
Zhang holds a notable patent titled "Vectors and methods for the efficient generation of integration/transgene-free induced pluripotent stem cells from peripheral blood cells." This invention details a vector designed for generating induced pluripotent stem cells from human target cells. The patent outlines a novel vector backbone incorporated with two to four transcription and reprogramming factor genes, separated by a 2a self-cleavage peptide sequence. Additionally, it features a spleen focus-forming virus promoter and a post-transcriptional regulatory element Wpre, potentially combined with an anti-apoptotic factor gene. The method described involves transducing or transfecting target cells with these vectors, followed by their culture, ultimately leading to the generation of integration-free induced pluripotent stem cells.
Career Highlights
Zhang is affiliated with Loma Linda University, where he contributes significantly to advancing research in stem cell technology. His expertise and innovative mindset allow him to explore and develop methods that can revolutionize how stem cells are utilized in therapeutic applications.
Collaborations
Throughout his career, Xiaobing Zhang has collaborated with esteemed colleagues, including David J. Baylink and Kin-Hing William Lau. Together, they have worked on various projects that push the boundaries of their research capabilities, focusing on the integration of advanced technologies in regenerative medicine.
Conclusion
Xiaobing Zhang’s innovative work in developing integration-free induced pluripotent stem cells holds promise for the future of medical science. His contributions not only enhance our understanding of stem cell biology but also pave the way for new treatments and therapies that can benefit countless individuals in need. As the field of regenerative medicine evolves, inventors like Zhang play a crucial role in shaping its trajectory.