This inventor holds 2 USPTO granted patents. Top assignee: Miami University. Active years: 2018-2023.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2018-2023
Title: Innovations of Inventor Xiao-Wen Cheng
Introduction
Xiao-Wen Cheng is a notable inventor based in Oxford, OH (US). She has made significant contributions to the field of biotechnology, particularly in the development of plasmid vectors and recombinant baculovirus expression systems. With a total of two patents to her name, her work has implications for protein expression and genetic engineering.
Latest Patents
Xiao-Wen Cheng's latest patents include innovations related to donor plasmid vectors. These vectors, such as pFastBac™1 and pFastBac™ Dual, lack a cis DNA element upstream of the polh translation start codon (ATG) that is present in wild type multiple nucleopolyhedrovirus (AcMNPV). By inserting a cis DNA element upstream of the 50 bp polh promoter and replacing the SV40 pA with an AcMNPV polh pA signal, certain protein expression levels in High Five™ cells using the Bac-to-Bac® system can reach those of the wild type AcMNPV. Additionally, she has developed a recombinant baculovirus expression vector or cell that comprises an engineered baculovirus fp25k gene with modified or mutated spots, which include two 7-adenine mononucleotide repeats (MNR) and the 10TTAA site. The invention also outlines the method of making the vector and baculovirus.
Career
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile