Location History:
- Newton, MA (US) (2016)
- Weston, MA (US) (2016 - 2019)
- Cambridge, MA (US) (2018 - 2021)
Company Filing History:
7 out of 250 
4 out of 63 
1 out of 1,929 
Years Active: 2016-2025
Title: The Innovative Journey of Xianglin Shi
Introduction
Xianglin Shi, a distinguished inventor located in Cambridge, MA, has made significant contributions to the field of oligonucleotide synthesis. With seven patents to his name, he has demonstrated a commitment to advancing the methodologies in this critical area of research.
Latest Patents
Among his most recent innovations are two notable patents. The first patent focuses on "Convergent liquid phase syntheses of oligonucleotides," which details a novel process for manufacturing oligonucleotides through the coupling of multiple fragments. This method includes distinct reaction steps that contribute to the efficiency of oligonucleotide production. The second patent, titled "Synthesis of thiolated oligonucleotides without a capping step," introduces a solid-phase synthetic process that streamlines the preparation of thiolated oligonucleotides. This innovative method showcases a three-reaction cycle involving detritylation, coupling, and sulfurization, eliminating the need for a capping step, and holds potential for creating anti-sense oligonucleotides.
Career Highlights
Xianglin Shi has worked with prominent companies such as Biogen MA Inc. and Sunesis Pharmaceuticals, Inc. His experience in these organizations has provided him with a robust platform to explore and evolve his inventions, contributing to the broader scientific community.
Collaborations
Throughout his career, Shi has collaborated with esteemed colleagues like Brian T Hopkins and Timothy Raymond Chan. These partnerships have fostered an environment of innovation and knowledge sharing, essential for advancing research in oligonucleotide synthesis.
Conclusion
Xianglin Shi's contributions through his patents reflect a deep understanding of oligonucleotide synthesis and its applications. His innovative approaches not only enhance current methodologies but also pave the way for future advancements in the field. As he continues to explore new horizons in his research, the impact of his work will likely resonate within both academic and industrial contexts.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.