Location History:
- Hercules, CA (US) (2019)
- Albany, CA (US) (2014 - 2023)
Company Filing History:
Years Active: 2014-2025
Title: Xiangdong Meng: Innovator in Reverse Transcriptase Enhancement
Introduction
Xiangdong Meng is a prominent inventor based in Albany, CA (US). He has made significant contributions to the field of molecular biology, particularly in enhancing reverse transcriptase activity. With a total of 6 patents to his name, Meng's work has the potential to impact various applications in genetic research and diagnostics.
Latest Patents
One of Meng's latest patents focuses on compositions and methods for enhancing reverse transcriptase (RT) activity and reducing the inhibition of RT by various inhibitors, such as formalin, tannic acid, and heparin. The patent outlines methods to reduce RT inhibition through the addition of potassium glutamate, histidine hydrochloride monohydrate, and poloxamer 188 to a reaction mixture containing a polymerase. Additionally, it describes how RT can be enhanced by incorporating polyvinyl sulfonic acid sodium salt (PVSA) into the reaction mixture. The patent also provides oligonucleotide primers designed for reverse transcription of target sequences, which can have either high or low GC content. These innovations aim to improve RT yield, sensitivity, and tolerance to various chemicals.
Career Highlights
Xiangdong Meng is currently associated with Bio-Rad Laboratories, Inc., a company known for its advancements in life science research and clinical diagnostics. His work at Bio-Rad has allowed him to further develop his innovative ideas and contribute to the scientific community.
Collaborations
Meng has collaborated with notable colleagues, including Yanhong Kong and Steven Okino. These partnerships have likely facilitated the exchange of ideas and fostered advancements in their respective research areas.
Conclusion
Xiangdong Meng's contributions to enhancing reverse transcriptase activity through innovative methods and compositions highlight his role as a key inventor in molecular biology. His work continues to pave the way for advancements in genetic research and diagnostics.