Company Filing History:
Years Active: 2007-2014
Title: Innovations of Xiang-Dong Lei
Introduction
Xiang-Dong Lei is a notable inventor based in West Hills, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of expression vectors and methods for epitope liberation. With a total of 3 patents, his work has implications for immunology and therapeutic applications.
Latest Patents
One of Xiang-Dong Lei's latest patents is focused on "Expression vectors encoding epitopes of target-associated antigens and methods for their design." This invention outlines methods for identifying polypeptides suitable for epitope liberation. The process includes identifying an epitope of interest, providing a substrate polypeptide sequence that allows for proteasome processing, and assaying for the liberation of the epitope. The invention also discusses vectors that include a housekeeping epitope expression cassette, which can be derived from target-associated antigens. Furthermore, it describes a method for activating T cells by contacting a substrate polypeptide with an antigen-presenting cell (APC) and subsequently with a T cell.
Career Highlights
Xiang-Dong Lei is currently associated with Mannkind Corporation, where he continues to innovate in the field of biotechnology. His work has been instrumental in advancing methods that enhance immune responses through targeted antigen presentation.
Collaborations
Some of his notable coworkers include John J L Simard and David C Diamond, who have collaborated with him on various projects within the biotechnology sector.
Conclusion
Xiang-Dong Lei's contributions to the field of biotechnology through his patents and collaborations highlight his role as a significant inventor. His work continues to influence advancements in immunology and therapeutic strategies.