Xianbin Tian is a prominent inventor based in Chapel Hill, NC (US). He has made significant contributions to the field of hepatocyte research, focusing on methods that enhance the understanding of biliary excretion processes. With a total of 2 patents, his work is paving the way for advancements in drug screening and liver function studies.

Latest Patents

Xianbin Tian's latest patents include innovative methods for inhibiting the expression of proteins in hepatocytes. One patent describes a method for screening candidate compounds for their susceptibility to biliary excretion by a hepatocyte transport protein. This method involves introducing RNA sequences that correspond to the coding strand of the gene encoding the transport protein into the hepatocyte. The second patent outlines a comprehensive approach to screening candidate compounds, which includes providing a culture of hepatocytes with a transport protein and determining the amount of the candidate compound in bile canaliculi. This method allows for the assessment of multiple candidate compounds in a single effort, enhancing the efficiency of drug development.

Career Highlights

Xianbin Tian is affiliated with the University of North Carolina at Chapel Hill, where he conducts his research. His work has garnered attention for its potential applications in pharmacology and toxicology, particularly in understanding how drugs are processed by the liver.

Collaborations

Xianbin collaborates with esteemed colleagues such as Peijin Zhang and Kim L R Brouwer. Their combined expertise contributes to the advancement of research in hepatocyte function and drug metabolism.

Conclusion

Xianbin Tian's innovative approaches in hepatocyte research are instrumental in enhancing our understanding of drug excretion processes. His contributions through patents and collaborations are vital for future advancements in the field.

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