Xavier Godron

Title: Xavier Godron: Innovator in Nucleic Acid Synthesis

Introduction

Xavier Godron is a prominent inventor based in Le Kremlin-Bicêtre, France. He has made significant contributions to the field of nucleic acid synthesis, holding a total of three patents. His work focuses on innovative methods that enhance the efficiency and effectiveness of oligonucleotide synthesis.

Latest Patents

One of Xavier Godron's latest patents is titled "One pot synthesis of sets of oligonucleotides." This invention is directed to methods for synthesizing multiple oligonucleotides within the same reaction vessel. The process involves providing various initiators attached to supports, each with a unique terminal nucleotide and 3-O-blocking group. The synthesis is achieved through repeated cycles of template-free enzymatic additions of 3'-O-blocked nucleoside triphosphates, which can be deblocked under specific conditions. Another notable patent is "Massively parallel enzymatic synthesis of nucleic acid strands." This invention outlines methods for the template-free enzymatic synthesis of different polynucleotides with predetermined sequences. It utilizes large-scale arrays of reaction sites, allowing for controlled deprotection and deblocking steps at user-selected sites.

Career Highlights

Xavier Godron is currently associated with Dna Script, a company that specializes in innovative DNA synthesis technologies. His work at Dna Script has positioned him as a key player in advancing nucleic acid synthesis methodologies.

Collaborations

Xavier collaborates with notable colleagues, including Adrian Horgan and Thomas Ybert, who contribute to the innovative environment at Dna Script.

Conclusion

Xavier Godron's contributions to nucleic acid synthesis through his patents and work at Dna Script highlight his role as a leading inventor in the field. His innovative approaches continue to shape the future of oligonucleotide synthesis.