Wouter De Laat

Title: Wouter De Laat: Innovator in Chromatin Analysis

Introduction

Wouter De Laat is a prominent inventor based in Rotterdam, Netherlands. He has made significant contributions to the field of genetic research, particularly in the analysis of chromatin interactions. With two patents to his name, De Laat's work is at the forefront of innovative methodologies in molecular biology.

Latest Patents

De Laat's latest patents include groundbreaking technologies in chromatin conformation capture. The first patent, titled "Circular Chromosome Conformation Capture (4C)," outlines a method for analyzing the frequency of interaction of a target nucleotide sequence with genomic loci. This method involves several steps, including providing a sample of cross-linked DNA, digesting it with a primary restriction enzyme, and amplifying the nucleotide sequences of interest. The second patent, "Capture and Characterized Co-localized Chromatin (4C) Technology," shares a similar methodology, emphasizing the importance of understanding the interactions between DNA sequences. Both patents contribute to advancing the understanding of genomic architecture and its implications in various biological processes.

Career Highlights

Wouter De Laat is affiliated with the Erasmus University Medical Center, where he conducts his research. His work has garnered attention for its innovative approach to studying chromatin interactions, which are crucial for understanding gene regulation and expression.

Collaborations

De Laat collaborates with notable colleagues in his field, including Frank Grosveld. Their combined expertise enhances the research output and fosters advancements in genetic analysis.

Conclusion

Wouter De Laat's contributions to the field of molecular biology through his patents and research at Erasmus University Medical Center highlight his role as an influential inventor. His innovative methodologies in chromatin analysis pave the way for future discoveries in genetics.