This inventor holds 2 USPTO granted patents and 2 published patent applications. Top assignee: University of Southern California. Active years: 2016-2020.
Company Filing History:
Years Active: 2016-2020
Title: Woojin An: Innovator in Cancer Research and Histone Proteolysis
Introduction
Woojin An is a prominent inventor based in Los Angeles, CA, known for his significant contributions to cancer research and the understanding of histone proteolysis. With a total of 2 patents, An has made strides in identifying critical mechanisms that influence gene regulation and cancer progression.
Latest Patents
An's latest patents include a method for identifying histone tail proteolysis and compositions for the treatment of VprBP-related cancers. The first patent details a novel approach called ChIP of acetylated chromatin (ChIPac), which allows for the identification and examination of H3NT-cleaved regions in mammals. This method revealed that H3NT proteolysis is selectively targeted near transcription start sites of specific genes, significantly impacting osteoclast differentiation. The second patent focuses on methods and compositions to inhibit VprBP kinase activity, providing new avenues for cancer treatment by suppressing tumor growth.
Career Highlights
Woojin An is affiliated with the University of Southern California, where he conducts his research. His work has been instrumental in uncovering the role of matrix metalloproteinase 9 (MMP-9) in osteoclastogenesis and its implications for gene regulation. An's findings emphasize the importance of H3NT proteolysis in regulating pathways essential for effective osteoclast differentiation.
Collaborations
An collaborates with notable colleagues, including Kyunghwan Kim and Nouri Neamati, to advance research in his field. Their combined expertise enhances the impact of their work on cancer research and histone biology.
Conclusion
Woojin An's innovative research and patents contribute significantly to the fields of cancer treatment and gene regulation. His work continues to pave the way for new therapeutic strategies and a deeper understanding of cellular processes.