Wolfgang Ch Poller

Title: Innovations in Cardiac Treatment by Wolfgang Ch Poller

Introduction

Wolfgang Ch Poller is a notable inventor based in Falkensee, Germany. He has made significant contributions to the field of cardiac treatment through his innovative research and patents. His work focuses on utilizing RNA interference to address heart failure, a condition that affects millions worldwide.

Latest Patents

Wolfgang Ch Poller holds a patent related to RNA interference for the treatment of heart failure. The invention involves targeted RNAi aimed at modulating defective cardiac calcium homeostasis by decreasing the expression or activity of phospholamban (PLB). This method utilizes adeno-associated virus (AAV) transfection of cardiomyocytes. The patent also discloses methods for reducing ventricular arrhythmias and improving overall survival rates in subjects suffering from heart failure. Additionally, it provides diagnostic methods for assessing susceptibility to RNAi treatment, along with pharmaceutical compositions, kits, and vectors that include an RNAi sequence. He has 1 patent to his name.

Career Highlights

Wolfgang Ch Poller is associated with Nanocor Therapeutics, Inc., where he continues to advance his research in cardiac therapies. His work is pivotal in developing innovative solutions for heart failure, which remains a critical area of medical research.

Collaborations

He has collaborated with esteemed colleagues such as Roger J Hajjar and Henry Fechner, contributing to the advancement of cardiac treatment methodologies.

Conclusion

Wolfgang Ch Poller's innovative work in RNA interference represents a significant advancement in the treatment of heart failure. His contributions are vital for improving patient outcomes and enhancing the understanding of cardiac health.