Company Filing History:
Years Active: 1980
Title: Wladyslawa Wagner: Innovator in Pharmaceutical Chemistry
Introduction
Wladyslawa Wagner is a notable inventor based in Warsaw, Poland. She has made significant contributions to the field of pharmaceutical chemistry, particularly through her innovative work on polyene macrolides. Her research has led to advancements in the treatment of fungal infections, showcasing her expertise and dedication to improving healthcare.
Latest Patents
Wladyslawa Wagner holds a patent for "Salts of N-glycosyl derivatives of polyene macrolides." This patent describes new compounds, specifically N-methylglucamine salts of N-glycosyl derivatives of polyene macrolides, including amphotericin B, polifungin, and nystatin. These compounds exhibit high pharmacological activity against certain topical and systemic fungal infections. The preparation involves a reaction between an amino group-containing polyene macrolide and an aldose or ketose mono- or oligosaccharide in an organic solvent medium. The resulting N-glycosyl derivatives are precipitated from the reaction medium and transformed into N-methylglucamine salts, which are then crystallized from higher alkanols.
Career Highlights
Wladyslawa Wagner has worked at prominent institutions such as Politechnika Gdańska and the Pharmaceutical Industry Institute. Her work at these organizations has allowed her to collaborate with other experts in the field and contribute to significant advancements in pharmaceutical research.
Collaborations
Wladyslawa has collaborated with notable colleagues, including Leonard S. Falkowski and Zuzanna Kowszyk-Gindifer. These collaborations have enriched her research and expanded the impact of her innovations in the pharmaceutical industry.
Conclusion
Wladyslawa Wagner's contributions to pharmaceutical chemistry, particularly through her patent on N-glycosyl derivatives of polyene macrolides, highlight her role as an innovator in the field. Her work continues to influence the treatment of fungal infections and showcases the importance of research and collaboration in advancing healthcare solutions.