Company Filing History:
Years Active: 2001-2010
Title: William Thomas Melvin: Innovator in Cancer Diagnostics
Introduction
William Thomas Melvin is a notable inventor based in Aberdeen, GB. He has made significant contributions to the field of cancer diagnostics, holding a total of four patents. His work focuses on identifying novel biomarkers and therapeutic interventions for various cancers.
Latest Patents
One of Melvin's latest patents involves mitochondrial stress-70 protein markers for colorectal cancer. This invention provides previously uncharacterized markers of cancers, particularly colorectal cancers, and outlines their use as diagnostic and prognostic markers. The markers include SEQ ID NO: 1—hnRNP-K; SEQ ID NO: 2—HMG-1; SEQ ID NO: 3—proteasome subunit alpha type 1; SEQ ID NO: 4—bifunctional purine biosynthesis protein; SEQ ID NO: 5—ST11; SEQ ID NO: 6—annexin IV; SEQ ID NO: 7—60 kDa heat shock protein; SEQ ID NO: 8—T complex protein 1 beta subunit; SEQ ID NO: 9—T complex protein 1 epsilon subunit; SEQ ID NO: 10—mortalin; and SEQ ID NO: 11—TER-ATPase. This invention also provides methods and materials for using these markers in therapeutic interventions, specifically targeting neoplastic cells while minimizing toxicity to healthy tissues. Another significant patent involves antibodies specific for CYP1B1, which can bind to cytochrome P450 CYP1B1. These antibodies are useful in diagnosing or treating cancers associated with enhanced CYP1B1 expression, including breast, prostate, colorectal, liver, and ovarian cancers.
Career Highlights
Melvin has worked with the University Court of the University of Aberdeen, contributing to research and development in cancer diagnostics. His innovative work has positioned him as a key figure in the field, particularly in the development of targeted therapies.
Collaborations
Some of his notable coworkers include Graeme Ian Murray and Michael Danny Burke. Their collaborative efforts have further advanced the research and application of cancer diagnostics.
Conclusion
William Thomas Melvin's contributions to cancer diagnostics through his innovative patents highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in cancer treatment
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