This inventor holds 1 USPTO granted patent. Top assignee: University of California. Active years: 1998.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1998
Title: The Innovations of William Searles
Introduction
William Searles is a notable inventor based in Fremont, California. He has made significant contributions to the field of mass spectrometry, particularly in the analysis of large molecules. His innovative work has led to the development of a unique apparatus that enhances the capabilities of mass spectrometers.
Latest Patents
William Searles holds a patent for an "Apparatus and method of determining molecular weight of large molecules." This invention involves a mass spectrometer that determines the mass of multiply charged high molecular weight molecules. The spectrometer utilizes an ion detector capable of simultaneously measuring the charge z and transit time of a single ion as it passes through the detector. From this transit time, the velocity of the single ion can be derived, providing the mass-to-charge ratio m/z for a single ion accelerated through a known potential. With the values of z and m/z, the mass m of the single ion can be calculated. This technology allows for the detection of electrospray ions with masses exceeding 1 MDa and charge numbers greater than 425 e.sup.-. The on-axis single ion detection configuration enables a duty cycle of nearly 100%, extending the practical application of electrospray mass spectrometry to the analysis of very large molecules with relatively inexpensive instrumentation.
Career Highlights
William Searles is affiliated with the University of California, where he continues to advance research in mass spectrometry. His work has been instrumental in improving the analysis of large biomolecules, which is crucial for various scientific fields, including biochemistry and pharmaceuticals.
Collaborations
Throughout his career, William has collaborated with esteemed colleagues such as Stephen Fuerstenau and W. Henry Benner. These collaborations have further enriched his research and contributed to the advancement of mass spectrometry technologies.
Conclusion
William Searles is a pioneering inventor whose work in mass spectrometry has significantly impacted the analysis of large molecules. His innovative patent demonstrates the potential for advancements in scientific research and practical applications in various industries.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile