Company Filing History:
Years Active: 1992
Title: The Innovative Contributions of William R. Majarian
Introduction
William R. Majarian is a notable inventor based in Pittsford, NY (US). He has made significant contributions to the field of biotechnology, particularly in the development of vaccines. His work focuses on innovative solutions to combat malaria, a disease that poses a significant threat to global health.
Latest Patents
William R. Majarian holds a patent for "Vaccines for the malaria circumsporozoite protein." This invention is directed to attenuated strains of enteroinvasive bacteria that express a peptide or protein related to an epitope of the malaria parasites of the genus Plasmodium. The bacterial strains developed can multiply in a host without causing significant disease or disorder, while also expressing a Plasmodium-related peptide that induces a protective immune response against malaria. This invention can be utilized in live vaccine formulations for malaria, with specific embodiments involving the expression of a Plasmodium-related peptide as a fusion protein, such as with a bacterial enterotoxin. The invention also encompasses methods for the expression of malaria antigens or fragments within attenuated enteroinvasive bacteria, particularly focusing on the expression by attenuated Salmonella spp. of epitopes of Plasmodium circumsporozoite proteins.
Career Highlights
William R. Majarian is associated with Praxis Biologics, Inc., where he continues to advance his research and development efforts. His innovative approach to vaccine development has the potential to significantly impact public health and disease prevention strategies.
Collaborations
Some of his notable coworkers include Robert N. Brey, III and Subramonia Pillai, who contribute to the collaborative efforts in research and development within the company.
Conclusion
William R. Majarian's work exemplifies the spirit of innovation in the field of biotechnology. His contributions to malaria vaccine development highlight the importance of scientific research in addressing global health challenges.