William R Bachman

Title: The Innovations of William R. Bachman

Introduction

William R. Bachman is a notable inventor based in North Brunswick, NJ (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of innovative compositions that enhance drug delivery.

Latest Patents

Bachman holds a patent for "Pharmaceutical compositions in the form of beadlets and method." This invention provides a pharmaceutical composition that consists of a plurality of beadlets, which can be filled into hard shell capsules or compressed into tablets. The beadlets are formed from various pharmaceuticals, including ACE inhibitors like captopril, beta-blockers such as nadolol, propranolol, or atenolol, and calcium channel blockers like diltiazem or nifedipine. The composition also includes a binder, such as microcrystalline cellulose, and at least 5% by weight of an acid processing aid, such as citric acid, which enhances the plasticity of the wet mass for efficient extrusion and spheronization. The method for forming these beadlets involves extruding the composition and subjecting the resulting extrudate to a spheronization step.

Career Highlights

Bachman is associated with E. R. Squibb Sons, Inc., where he has contributed to various pharmaceutical innovations. His work has focused on improving the formulation and delivery of medications, which is crucial for patient compliance and therapeutic effectiveness.

Collaborations

Throughout his career, Bachman has collaborated with esteemed colleagues, including Yatindra M. Joshi and Nemichand B. Jain. These collaborations have fostered a productive environment for innovation and development in pharmaceutical sciences.

Conclusion

William R. Bachman is a distinguished inventor whose work in pharmaceutical compositions has the potential to significantly impact drug delivery systems. His innovative approach to creating beadlet formulations exemplifies the importance of research and development in the pharmaceutical industry.