Location History:
- Ann Arbor, MI (US) (1999 - 2001)
- La Honda, CA (US) (1999 - 2002)
Company Filing History:
Years Active: 1999-2002
Title: Innovations of William M Kelley
Introduction
William M Kelley is a notable inventor based in La Honda, California. He has made significant contributions to the field of biotechnology, particularly in the development of hybrid viral vectors. With a total of 4 patents, Kelley has been at the forefront of innovative research that has the potential to impact gene therapy and recombinant virus production.
Latest Patents
Kelley’s latest patents include the development of hybrid adenovirus-AAV virus constructs. These inventions provide a hybrid vector that comprises a portion of an adenovirus, along with 5′ and 3′ ITR sequences from an AAV, and a selected transgene. The hybrid vectors are designed to form a polycation conjugate and incorporate an AAV rep gene into a single particle. These vectors are characterized by their high titer transgene delivery to host cells and their ability to stably integrate the transgene into the host cell chromosome. Additionally, the use of these hybrid vectors allows for the production of large quantities of recombinant AAV.
Career Highlights
William M Kelley is affiliated with the University of Pennsylvania, where he conducts his research and development work. His innovative approaches in the field of gene therapy have garnered attention and recognition within the scientific community.
Collaborations
Kelley has collaborated with esteemed colleagues such as James M Wilson and Krishna J Fisher. These partnerships have further enhanced the scope and impact of his research endeavors.
Conclusion
William M Kelley is a prominent inventor whose work in hybrid viral vectors is paving the way for advancements in gene therapy. His contributions are significant and continue to influence the field of biotechnology.