Company Filing History:
4 out of 289 
3 out of 164 
2 out of 199 
Years Active: 1993-2008
Title: William M Gallatin: Innovator in Immunology
Introduction
William M Gallatin is a prominent inventor based in Mercer Island, WA (US). He has made significant contributions to the field of immunology, holding a total of 7 patents. His work focuses on therapeutic methods that modulate the immune response, particularly through the interaction of various cells and antibodies.
Latest Patents
Gallatin's latest patents include innovative methods for blocking the interaction between stromal cells and hemopoietic cells using anti-VCAM-1 antibodies. One of his notable therapeutic methods involves administering IL-4 to promote peripheral blood lymphocyte adhesion to microvascular endothelial cells in lymphoid organs. This method is enhanced by coadministering IL-1β. Additionally, he has developed an improved method for screening cell lines for binding partners that interact with cell adhesion molecules. This involves testing binding partners with IL4-activated and nonactivated microvascular endothelial cells, selecting those that specifically bind to the activated cells. The selected binding partners are then evaluated for their ability to block lymphocyte binding to cytokine-activated endothelial cells. A representative embodiment of this work is mAb 6G10, produced by hybridoma ATTC No. HB10519. Furthermore, he has devised methods for using agents that bind to VCAM-1 to impede the transmigration of lymphocytes across postcapillary venules.
Career Highlights
Throughout his career, Gallatin has worked with esteemed organizations such as the Fred Hutchinson Cancer Center and Icos Corporation. His research has significantly advanced the understanding of immune response modulation, making him a key figure in his field.
Collaborations
Gallatin has collaborated with notable colleagues, including Boris Masinovsky and Paul J Simmons. These partnerships have contributed to the success of his research and innovations.
Conclusion
William M Gallatin's contributions to immunology through his patents and research have made a lasting impact on the field. His innovative approaches to modulating the immune response continue to influence therapeutic methods today.