William Kelton

Title: The Innovations of William Kelton

Introduction

William Kelton is a notable inventor based in Basel, Switzerland. He has made significant contributions to the field of biotechnology, particularly in the development of mammalian cell lines for protein production. With a total of 2 patents, his work has the potential to impact various applications in medicine and research.

Latest Patents

Kelton's latest patents focus on a method for generating a mammalian cell line that enhances protein production. The process involves several steps, including providing a plurality of mammalian B cells with a transgenic genomic DNA sequence encoding a marker protein. This sequence is designed to be cleaved by a site-directed nuclease, specifically Cas9. The method further includes replacing the marker protein's encoding sequence with a second transgenic DNA sequence that encodes a protein of interest. Finally, B cells are sorted based on the presence or absence of the marker protein, allowing for the collection of B cells that lack the marker.

Career Highlights

William Kelton is affiliated with ETH Zurich, a prestigious research institution known for its cutting-edge advancements in science and technology. His work at ETH Zurich has positioned him as a key figure in the field of protein production and cell line development.

Collaborations

Kelton collaborates with esteemed colleagues such as Sai Reddy and Cristina Parola, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

William Kelton's contributions to biotechnology through his patents and research at ETH Zurich highlight his role as an influential inventor. His work in developing mammalian cell lines for protein production is paving the way for advancements in various scientific fields.