Mountain Lakes, NJ, United States of America

William J Houlihan


Average Co-Inventor Count = 1.5

ph-index = 9

Forward Citations = 278(Granted Patents)

Forward Citations (Not Self Cited) = 252(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • Mount Lakes, NJ (US) (1976)
  • Baden, OE (1976)
  • Lake Parsippany, NJ (US) (1978)
  • Mt. Lakes, NJ (US) (1979 - 1988)
  • Mountain Lake, NJ (US) (1990)
  • Mountain Lakes, NJ (US) (1976 - 1994)

Company Filing History:


Years Active: 1976-1994

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Areas of Expertise:
Heterocyclic Phospholipids
Triglyceride-Water Emulsion
Imidazo[2,1-a]Isoquinolines
Tricyclic Quinazolinones
Piperidine Alcohols
Substituted Benzimidazoles
Dibenz[c,f]Imidazo
Hydroxyalkyl Substituted Pyridazinones
Alkanoyl Substituted Benzoic Acids
Thioether Phospholipids
Aryl-Substituted Compounds
Biological Activity Compounds
74 patents (USPTO):Explore Patents

Title: William J. Houlihan: Innovator in Pharmaceutical Chemistry

Introduction

William J. Houlihan is a distinguished inventor based in Mountain Lakes, NJ, with an impressive portfolio of 74 patents. His contributions to pharmaceutical chemistry have significantly advanced the field, particularly in the development of innovative compounds and processes.

Latest Patents

Houlihan's recent patents showcase his expertise in stereochemistry and drug development. One notable invention is a process for preparing the (R) stereoisomer of 2,2-bis(hydroxymethyl)-tetrahydrofuran monobutyrate. This process involves subjecting the dibutyric ester of this compound to enzymatic hydrolysis, resulting in a novel (R) stereoisomer. The invention not only introduces more stable forms of this stereoisomer but also explores its application in preparing pharmacologically active compounds.

Another significant patent involves heterocyclic phospholipids that are useful in treating multiple sclerosis. This invention discloses a variety of heterocyclic, thioether, keto-ester, and alkyl phospholipids, which have demonstrated potential in the therapeutic landscape for managing this condition.

Career Highlights

Throughout his career, William J. Houlihan has been associated with notable companies such as Sandoz GmbH and Sandoz Pharmaceuticals Corporation. His work within these organizations has contributed to various advancements in drug development and innovation. His extensive patent portfolio reflects his commitment to research and development in the pharmaceutical industry.

Collaborations

During his career, Houlihan has collaborated with esteemed professionals, including Jeffrey Nadelson and George A. Cooke. These partnerships have likely played a crucial role in his innovative processes and advancements, allowing for a blend of expertise and creativity in addressing complex pharmaceutical challenges.

Conclusion

William J. Houlihan's contributions to the field of pharmaceutical chemistry through his numerous patents illustrate the importance of innovation in developing effective therapies. His work in creating and refining compounds continues to impact the landscape of medicine, showcasing the vital role of inventors in advancing health solutions.

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