William J Harrison

Title: The Innovations of William J Harrison in Optical Molecular Imaging

Introduction

William J Harrison, an accomplished inventor from Pittsford, NY, holds an impressive portfolio of 19 patents. His work primarily focuses on innovative advancements in optical molecular imaging, particularly through the use of fluorescent dyes and latex particles.

Latest Patents

Among his latest patents, Harrison introduced a groundbreaking invention titled "Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes." This invention involves a loaded particle that includes at least one fluorescent dye, specifically targeting dyes with a large Stokes shift. Notably, the patent discusses a method for producing a loaded latex particle infused with this fluorescent dye, emphasizing that these dyes can exhibit increased quantum yield of fluorescence when compared to their performance in aqueous solvents.

Another significant patent by Harrison centers around "Large stoke shift dye used for optical imaging." This diagnostic contrast agent comprises a water-dispersible, near-infrared tricarbocyanine dye with an enamine functionalization, boasting a Stokes shift exceeding 50. The invention also details a method for creating a dye-conjugate using this innovative dye and a method for identifying biological compounds through the novel dye conjugate.

Career Highlights

Harrison has significantly impacted the field of molecular imaging throughout his career. He has worked with esteemed companies, including Eastman Kodak Company and Bruker Biospin GmbH. His contributions have not only earned him numerous patents but have also positioned him as a leading figure in optical imaging research.

Collaborations

Throughout his professional journey, Harrison collaborated with notable colleagues such as Richard L Parton and Margaret Jones Helber, further enhancing the innovative spirit of his research endeavors. These collaborations have played a crucial role in advancing the applications of his inventions within the scientific community.

Conclusion

William J Harrison's accomplishments in the realm of patents and inventions demonstrate his commitment to pioneering advancements in optical molecular imaging. His innovative approaches to using fluorescent dyes and loaded latex particles have the potential to revolutionize diagnostic methods in biological research, making him a significant contributor to the field of science.