This inventor holds 50 USPTO granted patents and 5 published patent applications, plus 1 CIPO patent and 3 EPO patents, primarily in Implantable Medical Devices. Top assignees: Medtronic, Inc., 3Dt Holdings, LLC, C. R. Bard, Inc.. Active years: 1986-2025.
Location History:
- Shoreview, MN (US) (1986)
- Minneapolis, MN (US) (1990)
- Eden Prairie, MN (US) (1994 - 2003)
- Eden Prarie, MN (US) (1999 - 2003)
- Minnetonka, MN (US) (2003 - 2015)
- Galena, OH (US) (2016 - 2023)
Company Filing History:
40 out of 8,944 
4 out of 62 
4 out of 1,760 
Years Active: 1986-2025
Areas of Expertise:
Title: Innovator Spotlight: William J. Combs
Introduction
William J. Combs, based in Minnetonka, MN, is a prolific inventor with an impressive portfolio of 49 patents. His groundbreaking work primarily focuses on medical devices, particularly in the fields of catheter navigation and luminal organ analysis. Combs has significantly contributed to advancements in healthcare technology, improving patient outcomes through innovative medical solutions.
Latest Patents
Among his latest patents are two noteworthy inventions that illustrate his expertise in medical technology. The first, titled "Apparatus and methods relating to intravascular positioning of distal end of catheter," outlines systems and methods for the effective navigation and positioning of a central venous catheter within a patient. This innovative system consists of a dual-pole setup designed to generate an electric field that enables the acquisition of multiple field measurements. It incorporates a stylet with a magnetic assembly positioned at its distal end, functioning as both an excitation and detection electrode. The advancement of the medical device within the patient is facilitated by utilizing a conductance curve derived from the collected measurements to identify potential obstructions or malpositions.
The second patent, "Luminal impedance device with integrated circuit modules," details impedance devices complemented by integrated circuit modules, providing a method for obtaining critical luminal organ information. This device features an elongated body designed for partial insertion into a mammalian luminal organ, comprising a first conductor for delivering power and a sensor substrate situated near its distal end. This innovative design allows the collection of vital sizing and pressure data, which are transmitted back to the proximal electrical unit for analysis.
Career Highlights
Throughout his career, William J. Combs has made significant contributions while working with leading companies in the medical device industry, including Medtronic, Inc. and 3DT Holdings, LLC. His roles at these organizations have enabled him to leverage his inventions into practical applications that enhance the field of medicine.
Collaborations
Combs' success has been bolstered by collaborations with esteemed colleagues such as H. Toby Markowitz and Ghassan S. Kassab. Their collective expertise has undoubtedly played a role in the development of his innovative patents, showcasing the power of teamwork in driving technological advancement.
Conclusion
William J. Combs stands out as a significant figure in the realm of medical innovation. His 49 patents reflect a dedication to enhancing patient care through technology. As the healthcare landscape continues to evolve, Combs' contributions will undoubtedly leave a lasting impact, inspiring future generations of inventors in the medical device field.