Company Filing History:
Years Active: 1982-1985
Title: Innovations of William H Holleman
Introduction
William H Holleman is a notable inventor based in Libertyville, IL (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of materials and methods for medical applications. With a total of 2 patents, his work has the potential to impact various medical treatments and diagnostics.
Latest Patents
One of Holleman's latest patents is titled "Matrix polymers for binding endotoxins." This invention discloses an endotoxin binding material affixed to a support. One embodiment involves a matrix material capable of binding endotoxins, which comprises a polar, water-insoluble, high molecular weight polymer support. This support is attached to groups that adsorb endotoxin molecules, which consist of bifunctional aliphatic molecules. One end of these molecules is bound to the support, while the other end is bound to an aryl molecule. The invention is useful for removing endotoxins from biological fluids and other solutions, as well as for concentrating endotoxins for subsequent detection and quantification.
Another significant patent by Holleman is "Modified urokinase having extended activity and method of making." This patent describes a structurally modified urokinase that remains biologically active over an extended time period compared to native urokinase. The extended activity allows for the administration of lower doses of urokinase in the treatment of thromboembolic diseases. The patent also outlines methods for appropriately modifying the structure of urokinase.
Career Highlights
William H Holleman is associated with Abbott Laboratories Corporation, a leading company in the healthcare sector. His work at Abbott has allowed him to focus on innovative solutions that address critical medical challenges.
Collaborations
Throughout his career, Holleman has collaborated with notable colleagues, including Ronald Lee Gendrich and Shaw-guang Lee. These collaborations have contributed to the advancement of his research and the successful development of his patents.
Conclusion
William H Holleman is a distinguished inventor whose work in the field of biomedical engineering has led to significant advancements in medical treatments. His innovative patents demonstrate his commitment to improving healthcare solutions.