Company Filing History:
Years Active: 2001-2007
Title: Innovations of William F Kolbe
Introduction
William F Kolbe is an accomplished inventor based in Moraga, CA (US). He has made significant contributions to the field of biological crystallography, holding a total of three patents. His work focuses on enhancing the efficiency and reliability of protein characterization efforts.
Latest Patents
One of Kolbe's latest patents is an integrated crystal mounting and alignment system for high-throughput biological crystallography. This innovative method and apparatus facilitate the transportation, remote and unattended mounting, and visual alignment and monitoring of protein crystals for synchrotron-generated x-ray diffraction analysis. The protein samples are maintained at liquid nitrogen temperatures throughout the entire process, including shipment, mounting, alignment, data acquisition, and removal. The system ensures that samples are stably aligned to within a few microns at a specific point in space. This capability to perform tasks remotely and automatically significantly increases sample throughput and reliability for high-volume protein characterization efforts. Additionally, the design allows for a large number of samples to be shipped in a single cryogenic shipping container, as the protein samples are placed in a shipping-compatible layered stack of sample cassettes.
Career Highlights
William F Kolbe is affiliated with the University of California, where he continues to contribute to advancements in his field. His innovative work has garnered attention and respect within the scientific community.
Collaborations
Kolbe has collaborated with notable colleagues, including Bernard D Santarsiero and Raymond C Stevens, further enhancing the impact of his research and inventions.
Conclusion
William F Kolbe's contributions to biological crystallography through his innovative patents demonstrate his commitment to advancing scientific research. His work not only improves the efficiency of protein characterization but also sets a standard for future innovations in the field.
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