Company Filing History:
Years Active: 1990-2000
Title: Innovations by William E. Benitz
Introduction
William E. Benitz is a notable inventor based in Palo Alto, California. He has made significant contributions to the field of medical diagnostics, particularly in the area of infection detection in vulnerable populations. With a total of 2 patents, his work has the potential to improve patient outcomes in critical care settings.
Latest Patents
One of his latest patents is a rapid assay for infection in neonates. This innovative assay allows for the diagnosis of infections in immunodeficient patients, such as neonates or those with compromised immune systems. By enabling diagnosis at the initial evaluation, it helps avoid unnecessary antibiotic treatment and confinement to intensive care units for uninfected patients. The assay is capable of detecting bacterial, viral, or fungal colonization in the bloodstream, cerebrospinal fluid, or urinary tract, making it particularly useful for diagnosing sepsis. The method involves measuring polymorphonuclear leukocyte (PMN, neutrophil) CD11b levels using flow cytometry or laser scanning microscopy on low volume whole blood samples.
Another significant patent by Benitz is related to a smooth muscle cell growth inhibitor. This invention discloses an epithelium-derived inhibitor that can effectively inhibit the growth of smooth muscle cells. The inhibitor comprises a heparan sulfate proteoglycan and has been shown to release a glycosaminoglycan chain with growth-inhibiting activity. The purification methods for this substance are also detailed, highlighting its potential applications in various techniques for inhibiting smooth muscle cell growth.
Career Highlights
William E. Benitz is affiliated with Leland Stanford Junior University, where he continues to contribute to research and innovation in medical science. His work has garnered attention for its practical applications in healthcare, particularly in improving diagnostic methods for critically ill patients.
Collaborations
Throughout his career, Benitz has collaborated with esteemed colleagues, including Merton Bernfield and Erica E. Weirich. These collaborations have further enriched his research and contributed to the advancement of medical diagnostics.
Conclusion
William E. Benitz's contributions to medical diagnostics through his innovative patents demonstrate his commitment to improving patient care. His work in developing rapid assays and growth inhibitors showcases the potential for significant advancements in healthcare.