Wilhelm Haas

Title: Innovations of Wilhelm Haas in Mass Spectrometry

Introduction

Wilhelm Haas is a notable inventor based in Cambridge, MA, who has made significant contributions to the field of mass spectrometry. With a total of six patents to his name, Haas has focused on developing advanced reagents that enhance the capabilities of mass spectrometry techniques.

Latest Patents

Haas's latest patents revolve around the design of mass spectrometry tags. These tags are engineered to include a linker region, a mass balance region, and a reporter region. The innovative aspect of these tags is their ability to fragment in a mass spectrometer through an energy-dependent process, resulting in the production of multiple reporter molecules. Specifically, the reporter region is designed to yield at least two reporter molecules upon fragmentation. Furthermore, some regions of the tag may incorporate heavy isotopes, which enable the differentiation of these tags from others with similar mass-to-charge ratios. This unique capability allows for greater multiplexing capacity compared to conventional systems.

Career Highlights

Throughout his career, Wilhelm Haas has worked with prestigious institutions such as Harvard College and Dana-Farber Cancer Institute. His work in these organizations has contributed to advancements in cancer research and analytical chemistry.

Collaborations

Haas has collaborated with esteemed colleagues, including Steven P. Gygi and Martin Helmut Wuhr. These partnerships have fostered a collaborative environment that promotes innovation and the sharing of ideas in the scientific community.

Conclusion

Wilhelm Haas's contributions to mass spectrometry through his innovative patents and collaborations highlight his role as a leading inventor in the field. His work continues to influence advancements in analytical techniques and cancer research.