Company Filing History:
Years Active: 2017-2020
Title: Wesley Freund: Innovator in Nicotine Synthesis
Introduction
Wesley Freund is a notable inventor based in Arden, NC (US), recognized for his contributions to the field of nicotine synthesis. With a total of four patents to his name, Freund has made significant strides in developing methods for preparing and resolving nicotine enantiomers.
Latest Patents
Freund's latest patents focus on the synthesis and resolution of nicotine. The disclosed methods involve preparing nicotine and enriching the (S)(−) enantiomer. This process includes combining N-methyl-2-pyrrolidone or a salt thereof with a nicotinate compound in the presence of a solvent and a strong base. The result is the formation of 1-methyl-3-nicotinoyl-2-pyrrolidone or a salt thereof. Subsequently, this compound is reduced in solution with NaSO to produce racemic nicotine or its salt. The resolution of racemic nicotine may involve combining it with (−)-O,O'-di-p-toluoyl-L-tartaric acid (L-PTTA).
Career Highlights
Throughout his career, Wesley Freund has worked with various companies, including Njoy, Inc. and Covalent Research Technologies, LLC. His work has contributed to advancements in nicotine research and applications, showcasing his expertise in the field.
Collaborations
Freund has collaborated with notable